Maxiflox contains Moxifloxacin, a fluoroquinolone antibiotic. Its antibacterial effect comes from inhibiting bacterial topoisomerase II (DNA gyrase) and topoisomerase IV, enzymes critical for bacterial DNA replication, transcription, repair, and cell division.
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Maxiflox Ophthalmic Solution is prescribed for the treatment of bacterial conjunctivitis caused by susceptible strains of both Gram-positive and Gram-negative bacteria, as well as Chlamydia trachomatis. It is also available as an intraocular injection to prevent postoperative bacterial endophthalmitis.
Always use under the guidance of a registered physician.
Gram-positive bacteria:
Gram-negative bacteria:
Other microorganisms:
Intraocular use:
Avoid prolonged use to prevent overgrowth of resistant organisms, including fungi
Discontinue if superinfection occurs and start alternative therapy
Patients should avoid contact lens use during active conjunctivitis
Clinical evaluation may include slit lamp examination and fluorescein staining
Ocular adverse effects (1–6% of patients) may include:
Non-ocular effects (1–4% of patients) may include:
No formal drug-drug interaction studies have been conducted with Maxiflox ophthalmic solution
In vitro studies suggest Maxiflox does not affect CYP450 enzymes, making it unlikely to interfere with drugs metabolized by CYP3A4, CYP2D6, CYP2C9, CYP2C19, or CYP1A2
Allergy to Moxifloxacin, other quinolones, or any component of the medication
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